Abstract
The conversion of (-)-cis-carveol and (+)-cis-carveol by Streptomyces bottropensis SY-2-1 and S. ikutamanensis Ya-2-1 was investigated.
S. bottropensis SY-2-1 transformed (-)-cis-carveol mainly to (+)-bottrospicatol [(4R, 6R, 8R)-(+)-6, 8-oxidomenth-1-en-9-ol] (1), with (+)-isobottrospicatol [(4R, 6R, 8S)-(+)-6, 8-oxidomenth-1-en-9-ol] (2) as one of the minor products. On the other hand, strain SY-2-1 transformed (+)-cis-carveol mainly to (-)-isobottrospicatol (4), with (-)-bottrospicatol (3) as one of the minor products. S. ikutamanensis Ya-2-1 metabolized the cis-carveols in the same way into bottrospicatols.
The metabolic pathways for (-)-cis-carveol and (+)-cis-carveol in S. bottropensis SY-2-1 and S. ikutamanensis Ya-2-1, and the biological activities of bottrospicatols are described in this paper.
