Agricultural and Biological Chemistry
Online ISSN : 1881-1280
Print ISSN : 0002-1369
ISSN-L : 0002-1369
Distribution of the Methylcitric Acid Cycle and β-Oxidation Pathway for Propionate Catabolism in Fungi
Shunichi MIYAKOSHIHiroo UCHIYAMATakashi SOMEYATakayori SATOHTakeshi TABUCHI
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1987 年 51 巻 9 号 p. 2381-2387

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The distribution of the methylcitric acid cycle and the modified β-oxidation pathway for propionate catabolism was surveyed in yeasts and filamentous fungi, mainly by comparing the activities of the key enzymes. All the six tested species of filamentous fungi belonging to five genera and 21 species of yeasts belonging to eleven genera were found to catabolize propionate through the methylcitric acid cycle, with the exception of Candida rugosa and one group of strains of C. catenulata, which catabolize propionate through the β-oxidation pathway. From the observed diversity of propionate catabolism among closely related strains or species, it was assumed that different minor pathways evolved from universal metabolic pathways, such as the citric acid cycle and the β-oxidation pathway for fatty acids, in later stages of an evolutionary history.

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© Japan Society for Bioscience, Biotechnology, and Agrochemistry
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