Novel Triterpenoids and a Steroid from the Fungus Ganoderma lucidum

Abstract

Four novel triterpenoids, epoxyganoderiol A (1), B (2) and C (3) and ganoderal B (4), and one novel steroid (6) were isolated from the fungus Ganoderma lucidum, with the known ganoderol B (5) and 6β-hydroxy-ergosta-4, 7, 22-trien-3-one (7). Their structures were determined by spectroscopic methods. The absolute configuration of the α, β-epoxy alcohol moiety of 1-3 was elucidated by the lanthanide-induced Cotton effect in the CD spectrum.