A β-Hydroxychalcone and Flavonoids from Alfalfa Callus Stimulated by a Fungal Naphthoquinone, PO-1

Abstract

A fungal naphthoquinone, PO-1, was rapidly absorbed by alfalfa callus, and a prominent accumulation of 4', 7-dihydroxyflavone, 1-(2, 4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-1, 3-propanedione and 6-hydroxy-4', 7-dimethoxyisoflavone was seen in the PO-1-treated callus. This 1, 3-propanedione (β-hydroxychalcone) showed pronounced antifungal activity.