Agricultural and Biological Chemistry
Online ISSN : 1881-1280
Print ISSN : 0002-1369
ISSN-L : 0002-1369
Aromatic Side Chain Analogs of Cationomycin and Their Biological Activities
Makoto UBUKATATomoko AKAMAKiyoshi ISONO
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1988 年 52 巻 7 号 p. 1637-1641

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The aromatic side chain of cationomycin (1) was modified by the coupling the sodium salt of deacylcationomycin (2) with several aromatic carboxylic acids. There was a linear relationship between the logarithmic reciprocal minimal inhibitory concentration of the derivatives against Bacillus subtilis IFO 3513 and the logarithmic transport efficiency for the sodium ion. The anticoccidial activity of the anisyl analog (3) was higher than that of the parent compound (1).
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