Antifungal Activities of α-Isocyano-β-phenylpropionamides

Abstract

A variety of α-isocyano-β-phenylpropionamides were synthesized and their inhibitory activities examined against Sphaerotheca fuliginea and Cladosporium fulvum. Among them, N-cyclohexyl-α-isocyano-β-phenylpropionamide (3c) was chosen as the first candidate for an anti-Sphaerotheca fuliginea agent and exhibited about 2 times more potent activity than dinocap in a field test using cucumber plants.