Synthesis and Biological Activity of 6-O-(3-Acyloxytetradecanoyl)-N-acetyl-muramoyl Dipeptide Methyl Esters and Related Compounds

Hideharu ISHIDA; Kyoko TAKADA; Koji KIGAWA; Yasuyuki IMAI; Makoto Kiso; Akira HASEGAWA; Ichiro AZUMA

doi:10.1271/bbb1961.53.1269

Agricultural and Biological Chemistry

Online ISSN : 1881-1280
Print ISSN : 0002-1369
ISSN-L : 0002-1369

Synthesis and Biological Activity of 6-O-(3-Acyloxytetradecanoyl)-N-acetyl-muramoyl Dipeptide Methyl Esters and Related Compounds

Hideharu ISHIDA, Kyoko TAKADA, Koji KIGAWA, Yasuyuki IMAI, Makoto Kiso, Akira HASEGAWA, Ichiro AZUMA

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JOURNAL FREE ACCESS

1989 Volume 53 Issue 5 Pages 1269-1273

DOI https://doi.org/10.1271/bbb1961.53.1269

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Abstract

A variety of 6-O-(3-acyloxytetradecanoyl)-MDP methyl esters were synthesized using opticallyactive (3R)-3-acyloxytetradecanoic acid. Their immunoadjuvant activity was examined.

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