Enzymatic Production of D-Glycerate from L-Tartrate
1989 年 53 巻 8 号 p. 2101-2105
詳細
1989 年 53 巻 8 号 p. 2101-2105
D-Glyceric acid is a useful chiral synthon in synthetic organic chemistry. To produce D-glycerate cheaply, microorganisms that convert L-tartrate into D-glycerate with good yields and selectivity were isolated from soil samples. One microorganism obtained was identified as a strain of Pseudomonas sp. group Ve-2 and found to produce a new enzyme, L-tartrate decarboxylase. This enzyme catalyzes the direct conversion of L-tartrate into D-glycerate, with almost 100% selectivity. In the presence of a cell-extract of Pseudomonas sp. group Ve-2, the amount of D-glycerate produced from L-tartrate reached 53g/l under the best conditions examined, with a molar yield of almost 100% and an optical purity of more than 92% e.e.
この記事は最新の被引用情報を取得できません。
