(1S)-[1-2H]-sn-Glycerol (1a) was obtained in three steps from (6S)-[6-2H]-1, 6-anhydro-β-D-galactopyranose and converted to the (1R)-isomer (1b) via an SN2 reaction of a 1-O-methanesulfonylated derivative. The 1H and 13C-NMR spectra well characterized their structure and stereo-chemistry.
