δ-Acetyl-L-ornithyl-β-alanine Methyl Ester Hydrochloride, an Intermolecule Type Sweetener

Abstract

δ-Acetyl-L-ornithyl-β-alanine methyl ester is an un-sweet peptide as a salt-free compound with AH and X units among the sweetness-causing trifunctional units, AH, B, and X. However, it had sweetness when an acid component (i.e. HC1) as a B unit was added. We called peptide sweeteners, of which trifunctional units were located on more than one molecule, "Intermolecule type sweetener." In this investigation, we found that we could design sweeteners more easily by using the idea of intermolecule type sweetener system.