抄録
We screened for foodstuffs affecting interferon-β (IFN-β) production of human foreskin diploid fibroblasts, in the presence of poly I poly C, cycloheximide, and actinomycin D. α- and β-caseins stimulated IFN-β production dose-dependently, but κ-casein inhibited it. Of the two chymosin fragments of κ-casein, glycomacropeptide was an inhibitor but p-κ-casein was not. β-lactoglobulin stimulated IFN-β production weakly, but lactoferrin inhibited it strongly. It was also shown that serum contained some factors inhibiting IFN-β induction and stimulating its production.
