Synthesis and Biological Activity of the Functional Derivatives of 3- and 4-(Dimethylaminomethyl)-1, 2-dithiolanes

Abstract

A variety of derivatives of 3- and 4-(dimethylaminomethyl)-1, 2-dithiolanes were prepared as their biological equivalents in an analogous way to that for the nereistoxin derivatives. Most of them showed insecticidal and acaricidal activity. High potency against Chilo suppressalis was displayed by S, S'-[2-(dimethylaminomethyl)trimethylene] bis(thiobenzoate), and a broad spectrum of activity was observed for 5-(dimethylaminomethyl)-1, 2, 3-trithiane. The stereochemistry of the 1, 3-dithianes is also discussed.