Author's Organization：Department of Agricultural Chemistry, University of Osaka Prefecture Department of Agricultural Chemistry, University of Osaka Prefecture Research and Development Dept., Dainippon Seito Corp. Research and Development Dept., Dainippon Seito Corp. Department of Agricultural Chemistry, University of Osaka Prefecture Department of Agricultural Chemistry, University of Osaka Prefecture Department of Agricultural Chemistry, University of Osaka Prefecture Department of Agricultural Chemistry, University of Osaka Prefecture
A compound was isolated in crystal form from an extract of Gymnema sylvestre dried leaves. The compound was identified to be conduritol A by chemical methods, and the physicochemical characteristics also coincided with the data in the literature. Conduritol A was tested for its effect on intestinal glucose absorption or glucose tolerance in rats. The results show that the absorption of glucose in vitro was completely inhibited in the presence of 0.2 mg/ml of conduritol A and that the blood sugar level was effectively depressed by administering conduritol A at 10 mg/kg of rat body weight.
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