LC-MS Analysis and Structural Determination of New Amides from Javanese Long Pepper (Piper retrofractum)

抄録

Amides in a CH₂Cl₂ extract from the fruits of Piper retrofractum were detected by HPLC/APCI-MS. Seven new unsaturated amides, together with six known ones, were isolated, and their structures were determined to be N-isobutyl-2E, 4E, 12Z-octadecatrienamide (1), N-isobutyl-2E, 4E, 14Z-eicosatrienamide (2), 1-(octadeca-2E, 4E, 12Z-trienoyl)piperidine (3), 1-(eicosa-2E, 4E, 14Z-trienoyl)piperidine (4), 1-(octadeca-2E, 4E-dienoyl)piperidine (5), 1-(eicosa-2E, 4E-dienoyl)piperidine (6), and 1-(eicosa-2E, 14Z- dienoyl)piperidine (7) on the basis of chemical and spectroscopic evidence.