1994 Volume 58 Issue 1 Pages 189-190
All the lignans tested in a bioassay with Brassica campestris L. subsp. rapa Hook. fil. et ANDERS inhibited the root growth of this plant, except for deoxypicropodophyllin. The effects of functional groups in the molecule on the inhibitory activity of these compounds were studied. It is suggested that the methylenedioxyl group and the stereochemical configuration of the lactone junction of podophyllotoxin derivatives were closely related to the inhibitory activity. The O-methyl derivative of two hydroxyl groups of matairesinol greatly enhanced the inhibition of root growth in this plant.
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