Preparative-scale Chemo-enzymatic Synthesis of Optically Pure D-myo-Inositol-1-phosphate

Abstract

D-myo-Inositol-1-phosphate was synthesized by a short and facile route from optically pure 1D-1-acetoxy-4, 6-di-O-benzyl-myo-inositol, which was easily obtained by a highly regio- and enantioselective enzyme-catalyzed acetylation of 4, 6-di-O-benzyl-myo-inositol.