Author's Organization：Department of Chemistry and Materials Technology, Faculty of Engineering and Design, Kyoto Institute of Technology Department of Food Science and Technology, Faculty of Agriculture, Kyoto University Department of Food Science and Technology, Faculty of Agriculture, Kyoto University Department of Food Science and Technology, Faculty of Agriculture, Kyoto University
A 5'-flanking region (- 2024 to +61) of the guinea pig liver transglutaminase gene and some 5'-deletion mutants were tested for promoter activity in human hepatoblastoma HepG2 cells treated with interleukin-6 (IL-6) by an assay of the transient expression of the chloramphenicol acetyltransferase reporter gene. The promoter activity of the 5'-flanking region introduced into the HepG2 cells was increased by IL-6.
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