Preparation of Organic Solvent-Tolerant Mutants from Pseudomonas aeruginosa Strain PAO1161

抄録

Most organic solvents (OSs) are toxic and inhibit growth of microorganisms even at low concentrations. Therefore, they are used to sterilize microbial cultures and to maintain solutions in a sterile condition. However, the physiological basis of such phenomen is poorly understood. Although there are some microorganisms that can utilize a number of OSs as their sole carbon and energy sources, OSs must be provided as a vapor or at a very low concentration to avoid growth inhibition.