Isolation of Tautomycetin as a Regulator of Secondary Metabolite Production for Penicillium urticae

Shohei Sakuda; Kenji Miki; Shigeo Kitaoka; Marasri Reugjitchachawaly; Yasuhiro Yamada

doi:10.1271/bbb.59.133

Bioscience, Biotechnology, and Biochemistry

Online ISSN : 1347-6947
Print ISSN : 0916-8451

Isolation of Tautomycetin as a Regulator of Secondary Metabolite Production for Penicillium urticae

Shohei Sakuda, Kenji Miki, Shigeo Kitaoka, Marasri Reugjitchachawaly, Yasuhiro Yamada

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JOURNAL FREE ACCESS

1995 Volume 59 Issue 1 Pages 133-134

DOI https://doi.org/10.1271/bbb.59.133

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Abstract

Tautomycetin was isolated as a regulator of secondary metabolite production for Penicillium urticae. It induced the simultaneous production of a yellow compound, named patulodin, and of patulolides against P. urticae P3, which does not produce such metabolites under the usual conditions. Tautomycin, a phosphatase inhibitor, also caused the same phenomenon.

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