Microbial Transformation of Indene by the Pyricularia zingiberi Nishikado Fungus

Abstract

Indene was found to be microbially transformed to (-)-(1R, 2S)-cis-1, 2-indandiol (7.3% yield, 15% e.e.), (+)-(1R, 2R)-trans-1, 2-indandiol (3%) yield, 83% e.e.), (-)-(R)-indenol (0.1% yield, 89% e.e.), (+)-(S)-2-hydroxy-1-indanone (0.1% yield, 31% e.e.), 1-indanone (0.2% yield), and (+)-(S)-1-indanol (trace, 99% e.e.) by the Pyricularia zingiberi fungus.