Synthesis and Biological Activity of LL-P880γ and Its Analogues

Mitsunori KIRIHATA; Masayuki OHE; Itsuo ICHIMOTO; Yasuo KIMURA

doi:10.1271/bbb.60.677

Bioscience, Biotechnology, and Biochemistry

Online ISSN : 1347-6947
Print ISSN : 0916-8451

Synthesis and Biological Activity of LL-P880γ and Its Analogues

Mitsunori KIRIHATA, Masayuki OHE, Itsuo ICHIMOTO, Yasuo KIMURA

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Keywords: LL-P880γ synthesis, pestalotin analogues, gibberellin synergist, GA synergistic activity on rice seedlings, Penicillium species metabolite

JOURNAL FREE ACCESS

1996 Volume 60 Issue 4 Pages 677-679

DOI https://doi.org/10.1271/bbb.60.677

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Abstract

Stereoisomers and analogues of LL-P880γ (2) were synthesized and tested to elucidate its structure-activity relationship. Their evaluation in the gibberellin-synergistic assay with rice seedlings revealed a clear dependence of potency on the stereochemistry at C1′on the side chain of 2.

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