Synthesis and Antifungal Activity of Cinnamic Acid Esters

Shinkichi TAWATA; Shigehiko TAIRA; Naotada KOBAMOTO; Jun ZHU; Masanobu ISHIHARA; Seizen TOYAMA

doi:10.1271/bbb.60.909

Shinkichi TAWATA, Shigehiko TAIRA, Naotada KOBAMOTO, Jun ZHU, Masanobu ISHIHARA, Seizen TOYAMA

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Keywords: pineapple (Ananas comosus var. Cayenne), isopropyl 4-hydroxycinnamate, butyl 4-hydroxycinnamate, antifungal activity, Pythium sp., cinnamic acid

JOURNAL FREE ACCESS

1996 Volume 60 Issue 5 Pages 909-910

DOI https://doi.org/10.1271/bbb.60.909

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Abstract

Cininamic, p-coumaric and ferulic acids were isolated from pineapple stems (Ananas comosus var. Cayenne). Twenty-four kinds of esters were prepared from these acids, alcohols and the components of Alpinia. Isopropyl 4-hydroxycinnamate (11) and butyl 4-hydroxycinnamate (12) were found to have almost the same effectiveness in antifungal activity against Pythium sp. at 10 ppm as that of the commercial fungicide iprobenfos (Kitazin P).

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