Stimulation of Cytokine Gene Expression in a Murine Macrophage Cell Line by Lactic Acid Bacteria Isolated from Bhutanese Dried Yak Cheese

Yuji Ohashi; Kanako Nagai; Makoto Tokunaga; Kazunari Ushida; Tomomi Yamada

doi:10.12938/bifidus.24.125

Note

Stimulation of Cytokine Gene Expression in a Murine Macrophage Cell Line by Lactic Acid Bacteria Isolated from Bhutanese Dried Yak Cheese

Yuji Ohashi, Kanako Nagai, Makoto Tokunaga, Kazunari Ushida, Tomomi Yamada

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Keywords: lactic acid bacteria, cytokine, macrophage, fermented food

JOURNAL FREE ACCESS

2005 Volume 24 Issue 4 Pages 125-128

DOI https://doi.org/10.12938/bifidus.24.125

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Abstract

Lactic acid bacteria (LAB) isolated from dried yak cheese from the Bhutan Himalayas were examined for their ability to stimulate the expression of cytokine mRNA on the murine macrophage. The expression of tumor necrosis factor-α, interleukin (IL) 6 or IL-12 p40 gene was stimulated by several strains. The dried yak cheese, Chugo, contains LAB that possess immuno-modulating activity.

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