Successful Treatment by Probiotic Enema of Necrotizing Enterocolitis

Shoichi Ezaki; Kanako Itoh; Clara Kurishima; Masanori Tamura

doi:10.12938/bifidus.27.9

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Successful Treatment by Probiotic Enema of Necrotizing Enterocolitis

Shoichi Ezaki ^†, Kanako Itoh ^†, Clara Kurishima ^†, Masanori Tamura ^†

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Keywords: Bifidobacterium breve, probiotics, enema, necrotizing enterocolitis

JOURNAL FREE ACCESS

2008 Volume 27 Issue 1 Pages 9-11

DOI https://doi.org/10.12938/bifidus.27.9

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Abstract

We encountered a neonate with necrotizing enterocolitis (NEC) caused by Klebsiella pneumoniae. Clinical symptoms and inflammation did not improve despite intravenous administration of antibiotics. Bifidobacterium breve enemas were performed. After beginning enema, clinical symptoms and inflammation improved within 24 hours. Probiotic enema has high potential as a new therapy for NEC.

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