Abstract
By experiments on dogs the following results were obtained.
1. 3-4 days fasting has no marked influence upon the acetone forming function of the liver from butyric acid.
2. As far as my experimental results go, in dogs with obstructive jaundice or pancreas-diabetes the acetone forming function of the liver from butyric acid shows no marked difference compared with control animals.
3. In dogs poisoned with phosphorus, phenylhydrazine, toluilenediamine, carbon tetrachloride and chloroform the acetone forming function of the liver from butyric acid is lowered.
4. As far as butyric acid is concerned, a strict parallelism between the acetone forming function of the liver and its histologi-cal change is not proved.
I wish to express my gratitude to Prof. N. Kageura for suggesting this study and his guidance throughout the course of my research. My thanks are due to Dr. M. Hashiguchi and Dr. K. Inouein the Pathological Institute also for their help and advice in making the histological investigations herein reported.