PAPER CHROMATOGRAPHY OF SOME KETOBILE ACIDS
1952 年 39 巻 4 号 p. 333-337
詳細
1952 年 39 巻 4 号 p. 333-337
Zaffaroni's chromatographic method of developing Girard T hydrazone of ketosteroids was applied to ketobile acids, and similar results were obtained, confirming its applicability in this field.
1. After hydrazone formation, 14 kinds of ketobile acids syn-thetically prepared were chromatographically developed by n-butanol: iso-propanol: water (6:2:1) mixture by which separation was effected.
2. By this method, the ketobile acids possessing a ketone group in the 3-position are either totally undetected or they behave like the substances possessing one ketone group less than they actually have.
3. The effect of other polar groups than ketone groups, was found to be governed by a certain rule.
