Abstract
1. It was found that, by baker's yeast and Fleischmann's yeast, creatine in media was converted to creatinine accompanied by the fermentation of glucose, but to far less degree by the respiration.
2. Creatinine was not formed during the respiration of alcohol by yeast.
3. NaN3 completely inhibited the creatinine formation indicating that the process may have some correlation with the phosphorylation.
4. The amount of creatinine formed was nearly proportional to the amount of glucose and creatine present.
It will be interesting to investigate whether creatinine in animal urine may be formed by the similar process in animal body.