The Journal of Biochemistry
Online ISSN : 1756-2651
Print ISSN : 0021-924X
INHIBITION OF YEAST GLYCYLGLYCINE DIPEPTIDASE BY AMINO ACIDS
ARASUKE NISHI
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1960 年 47 巻 1 号 p. 47-53

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1. The inhibition of glycylglycine dipeptidase of yeast by various amino acids was investigated kinetically. The inhibition caused by L-leucine was competitive with substrate but not with Co++ ion. A scheme for the inhibition produced by amino acid was proposed which was shown to satisfactorily agree with the experimental results.
2. The inhibitory activities of various amino acids were compared in terms of the affinity constants of these substances towards the enzyme.
The author wishes to express his sincere gratitude to Prof. A. Takamiya for his valuable advices in this work.
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