抄録
Rats were anesthetized with ethylether or trichloroethylene to study the effects of those narcotics on the decomposition of acetoacetate in kidney slices or diaphragm under aerobic or anaerobic conditions, on the anaerobic pro-duction of β-hydroxybutyrate in kidney slices, and on the content of carbohydrate in diaphragm. The results were compared with those of control or epinephrinized rats and summarized as follows:
1. While the consumption of acetoacetate in kidney is lowered by ethylether or trichloroethylene anesthesia as well as by epinephrine administration. that in diaphragm is not influenced by these treatments.
2. Anaerobic production of β-hydroxybutyrate in kidney is increased by these treatments.
3. As regards the content of carbohydrate in the diaphragm, both free sugars and total carbohydrate decreased significantly in the epinephrinized group, whereas in the case of ethylether or trichloroethylene anesthesia the decrease of either free sugar or total carbohydrate alone was significant.
Thanks are due to Prof. Emeritus Y. Sueyoshi of the Keio University for invaluable advice and encouragement.
