Cation Carrier in the Erythrocyte Membrane
1962 年 52 巻 2 号 p. 99-102
詳細
1962 年 52 巻 2 号 p. 99-102
1. Regaining of potassium by cold-preincubated red cells was suppressed by 3×10-8 to 3×10-6M ouabain, while turnover of the phosphate moiety of phospholipids of red cell membrane, especially of phosphatidic acid, was not inhibited by ouabain.
2. Erythrocyte ATPase was inhibited by ouabain in the same range of concentration.
3. ATP added to the plasma inhibited potassium resorption from the plasma into the red cells.
4. Based on these results, a possibility was discussed for ATPase as playing a role in cation transport of red cells.
