Abstract
Recombination in meiosis is triggered at defined sites on chromosome called "hot spots", which can be found in accessible regions in chromosomes. Some factors for recombination and transcription are required for activation of recombination at hot spots. In fission yeast, a CREB/ATF-type transcription factor enhances recombination by remodeling local chromatin structure around a recombination hot spot, suggesting the relationship between transcription and recombination.
