2002 年 42 巻 6 号 p. 282-284
We developed a computer program, FAMS (Full Automatic Modeling System) to build model structures based on reference structures solved using X-ray diffraction, NMR or other experimental methods, and amino acid sequence alignment between a target and its reference structure. Its ability was clearly shown in the CAFASP2 competition1). FAMS produces a model whose torsion angles of the backbone and sidechain are highly accurate. The processes of the FAMS algorithm are fully automated and therefore don't require any special knowledge, techniques or experience to obtain a biologically worthwhile protein structure.