2013 年 53 巻 2 号 p. 090-093
Formation of synaptic connections between nerve cells is the key to understanding neuronal development. Despite the wealth of in vitro information, fundamental questions regarding how synapses are formed in the mammalian brain remain unanswered. Glutamate receptor (GluR) δ2 selectively expressed in cerebellar Purkinje cells is essential for synaptic formation in vivo. We showed that the trans-synaptic interaction of postsynaptic GluR