生物物理
Online ISSN : 1347-4219
Print ISSN : 0582-4052
ISSN-L : 0582-4052
特集:生物がみる光・生物をみる光~生物物理学を照らす七色の光~
蛍光および化学発光タンパク質の様々な応用
永井 健治松田 知己
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ジャーナル フリー

2015 年 55 巻 6 号 p. 305-310

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After the gene cloning and development of GFP color variants about 20 years ago, fluorescent and luminescent proteins have become indispensable tools for biological research. Their genetically encodablity and light-emitting property has revolutionized our research ability by allowing the visualization of variety of living specimen ranging from biochemical events, proteins, cells, and organisms. Detailed understanding of the physicochemical mechanisms responsible for light generation has helped drive performance improvements and application development. Here we will cover basics of light-emitting proteins, as well as the use of them for bioimaging and biomanipulation.

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© 2015 by THE BIOPHYSICAL SOCIETY OF JAPAN
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