2018 年 58 巻 4 号 p. 185-190
The rhodopsin research has been one of the major topics in the biophysical research field for more than 40 years. The discovery of channelrhodopsin was only the product of the rhodopsin research, but the successful application of channelrhodopsin in neurons in the early 2000s has dramatically changed the strategy in neuroscience research afterwards. As a matter of fact, the new scientific term optogenetics is now widely accepted in the neuroscience and the optogenetic manipulation is an essential tool to develop the field. The author reviews the history of optogenetics.