解説
骨格筋ミオシンにおける協同的な力発生機構
2019 年 59 巻 5 号 p. 241-247
詳細
2019 年 59 巻 5 号 p. 241-247
Despite numerous information on the molecular properties of skeletal myosin, its ensemble effects on collective force generation have not been rigorously clarified. This review introduces experimental and modeling approaches to investigate collective properties of skeletal myosin and explains how molecular properties of myosin are tuned to enhance the coordinated force generation among molecules. Such a cooperative force generation is essential for efficient muscle contractions.
