System Analysis of Multi-cellular Organization by Incorporating Control-sensing-information Technologies

Abstract

A multicellular organization is a complex system resulting from the orchestrating individual cellular migration to form a specific pattern. To elucidate the system, it is important to exert not only biological technologies but also control, sensing and information technologies. Controlling culture environments can enhance the repeatability of in vitro experimental result and add perturbation to validate the hypothesized theory. Large scale imaging at high resolution imaging provides comprehensive insight, and information systems lead us effective analysis from the obtained in vitro data. Once those technologies are well synchronized, we can open-up new insight.