ATPの反応性は何によって決定されているか
1988 年 28 巻 3 号 p. 131-134
詳細
1988 年 28 巻 3 号 p. 131-134
This paper deals with why the Pβ0-Pγ bond is cleaved specifically in the enzymic hydrolysis of ATP mediated by Mg2+. Mg2+ coordinates with the β-and γ-phosphoryl groups in such a way that it binds more strongly to the former. This asymmetric coordination weakens the bond where specific cleavage takes place in the enzyme catalyzed hydrolysis.
