抄録
Repetitive stimulation of the presynaptic nerve for a short time induces a long-term potentiation (LTP) of transmission at the excitatory glutaminergic synapses of the hippocampal formation. Mechanisms of LTPs, being a likely substrate for learning and memory, are discussed in terms of their induction, expression, and maintenance at pre-and postsynaptic sites of different types of synapse. Although cascades of LTP mechanisms are diversified among synapses, many common elementary processes are found to be shared by not only different hippocampal synapses but also other central and peripheral synapses.