酸性リン脂質分子集合体・ベシクル(リポソーム)の集合特性と熱力学的安定性
1994 年 34 巻 3 号 p. 109-116
詳細
1994 年 34 巻 3 号 p. 109-116
Spherical multilamellar vesicles of dimyristoylphosphatidylglycerol (DMPG) prepared in the presence of NaCl up to 1M at a temperature of liquid crystalline phase was found to exist in a metastable state at a gel phase temperature. On annealing at 5°C of the gel temperature, the metastable self-assemblies of DMPG converted finally into a stable state of crystalline cylindrical vesicular structure wrapped by 8-10 bilayer lamellae. The conversion process was discussed, focusing on the area occupied by negatively charged head group of DMPG molecules related to their packing modes.
