生理活性ペプチドおよびタンパク質前駆体のKex2様プロセシング酵素ファミリー
1994 年 34 巻 3 号 p. 124-130
詳細
1994 年 34 巻 3 号 p. 124-130
Endoproteolytic processing of precursor proteins typically at specific pairs of basic amino acids is a key step in the production of bioactive peptides and proteins. The endrproteases involved in this process belong to a new family of Ca2+ -dependent serine proteases related to the yeast Kex2 protease. These include furin, PC2, PC3, PC4, PACE4 and PC6, all of which have been characterized structurally and functionally.
