ジメチルオクタノールの合成およびそれらアルコールの香気について

抄録

Some kinds of dimethyl octanols which had partly the same molecular stucture with tetrahydrolinalool were prepared from corresponding ketones and n-alkylmagnesium halides respectively, and their odours were investigated. Some of the dimethyloctanols which had OH group in the same position of the carbon skeleton seemed to give similar odours, but this positional effect of functional group was not observed in the acetates of these dimethyloctanols. 7-Methyl-2-octanone which is intermediate substance for preparing 2,7-dimethyl-2-octanol giving rose-like-odour was synthesized from isobutylaldehyde as starting material by means of Grignard reaction with vinylmagnesiumchloride, Kimel reaction and catalytic hydrogenation succesively. The technique on preparing Grignard reagent with vinyl chloride was investigated.