Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
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Effect of Dried Fruits of Solanum nigrum LINN against CCl4-Induced Hepatic Damage in Rats
Kuppuswamy RajuGovindaraju AnbuganapathiVelusamy GokulakrishnanBalasubramanian RajkapoorBalasundarm JayakarSellamuthu Manian
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2003 Volume 26 Issue 11 Pages 1618-1619

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Abstract

Ethanol extract of Solanum nigrum LINN was investigated for its hepatoprotective activity against CCl4-induced hepatic damage in rats. The ethanol extract showed remarkable hepatoprotective activity. The activity was evaluated using biochemical parameters such as serum aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP) and total bilirubin. The histopathological changes of liver sample in treated animals were compared with respect to control.

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© 2003 The Pharmaceutical Society of Japan
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