Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
In Vitro Antioxidant Effect and Inhibition of α-Amylase of Two Varieties of Amaranthus caudatus Seeds
Filomena ConfortiGiancarlo StattiMonica Rosa LoizzoGianni SacchettiFerruccio PoliFrancesco Menichini
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2005 Volume 28 Issue 6 Pages 1098-1102


This study reports on the biological properties, antioxidant and antidiabetic, of two varieties of Amaranthus caudatus seeds, Oscar blanco and Victor red. Oil, squalene and phenolic contents were also determined. Seeds of both investigated varieties were found to possess very different levels of squalene (2.2% in Oscar blanco variety and 7.5% in Victor red variety). Although the antioxidant activity of A. caudatus var. Oscar blanco and A. caudatus var. Victor red statistically did not differ significantly from each other (IC50 values of ethyl acetate extracts were 0.50 mg/ml and 0.62 mg/ml, respectively), significant differences were noticed in relation to antidiabetic activity (inhibition of α-amylase, EC of methanolic extracts that showed 50.5% for A. caudatus var. Oscar blanco and 28% for A. caudatus var. Victor red at concentration of 25 μg/ml.

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© 2005 The Pharmaceutical Society of Japan
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