Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
Regular Articles
Synthesis and Analgesic Activity of 2-Phenoxybenzoic Acid and N-Phenylanthranilic Acid Hydrazides
Ali Almasirad, Rohollah Hosseini, Hassan Jalalizadeh, Zohreh Rahimi-Moghaddam, Nazila Abaeian, Maryam Janafrooz, Mohammad Abbaspour, Vahid Ziaee, Afshin Dalvandi, Abbas Shafiee
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Keywords: 2-phenoxybenzoic acid hydrazide, N-phenylanthranilic acid hydrazide, analgesic activity
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2006 Volume 29 Issue 6 Pages 1180-1185

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Abstract
A series of 2-phenoxybenzoic acid and N-phenylanthranilic acid hydrazides were synthesized and evaluated for their analgesic activities. Several compounds were significantly more potent than mefenamic acid and diclofenac sodium in abdominal constriction and formalin tests.
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© 2006 The Pharmaceutical Society of Japan
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