Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
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Susceptibilities of Methicillin-Resistant Staphylococcus aureus Isolates to Seven Biocides
Koji NaruiMitsuo TakanoNorihisa NoguchiMasanori Sasatsu
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2007 Volume 30 Issue 3 Pages 585-587

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Abstract
Minimum bactericidal concentrations (MBCs) of seven biocides for 42 methicillin-resistant Staphylococcus aureus (MRSA) isolates at 5, 30, or 180 min, for hand scrubs or soaks, isolated in 2003 in Japan were determined. The MBC values of glutaraldehyde, povidone iodine, and ethanol were lower than the user concentrations in all exposure times. However, at 5 min exposure of sodium hypochlorite, benzalkonium chloride, alkyldiaminoethylglycine hydrochloride, and chlorhexidine digluconate some strains showed higher MBC values than the user concentrations. These results indicated the possibility that MRSA survived under proper user concentration conditions and exposure time.
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© 2007 The Pharmaceutical Society of Japan
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