Inhibitory Effects of Three-Component Hybrid Liposomes Containing Cationic Lipids without Drugs on the Growth of Human Renal Tumor Cells in Vitro

Abstract

The inhibitory effects of three-component hybrid liposomes (HL) containing cationic lipids on the growth of human renal tumor cells were examined. Fifty percent inhibitory concentration of the three-component HL was remarkably reduced compared with that of dimyristoylphosphatidylcholine liposomes. The induction of apoptosis by the three-component HL without antitumor drugs was obtained for human renal tumor cells for the first time in this study.