著者所属：Research and Development Laboratories, Hoechst Japan Limited Research and Development Laboratories, Hoechst Japan Limited Research and Development Laboratories, Hoechst Japan Limited Research and Development Laboratories, Hoechst Japan Limited
The covalent binding ratio of cephalosporins (CEZ, CER, CET and CTX) to human serum albumin was examined at pH 7 and pH 10. The antibiotic equivalents were larger at pH 10 than at pH 7. The degree in the binding ratio of the 4 cephalosporins was CET>CER>CTX>CEZ at pH 7 and CER>CET>CTX>CEZ at pH 10.
