THE DEVELOPMENTAL PROCESS FROM MICELLE TO LIQUID CRYSTAL IN THE URSODEOXYCHOLATE, PHOSPHATIDYLCHOLINE AND CHOLESTEROL SOLUTION

HIROTSUNE IGIMI; SATOMI NISHIJIMA; HIDEHIKO SHIMURA

doi:10.1248/bpb1978.6.267

Journal of Pharmacobio-Dynamics

Online ISSN : 1881-1353
Print ISSN : 0386-846X
ISSN-L : 0386-846X

THE DEVELOPMENTAL PROCESS FROM MICELLE TO LIQUID CRYSTAL IN THE URSODEOXYCHOLATE, PHOSPHATIDYLCHOLINE AND CHOLESTEROL SOLUTION

HIROTSUNE IGIMI, SATOMI NISHIJIMA, HIDEHIKO SHIMURA

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Keywords: liquid crystal

JOURNAL FREE ACCESS

1983 Volume 6 Issue 4 Pages 267-271

DOI https://doi.org/10.1248/bpb1978.6.267

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Abstract

The developmental process from micelle to liquid crystal via the bilayer membrane is described based on electron microscopic observations using the freeze fracture method in solutions containing ursodeoxycholate, phosphatidylcholine and cholesterol. Comparisons of sodium tauroursodeoxycholate and sodium taurochenodeoxycholate solutions were performed and this developmental process was confirmed only in the sodium tauroursodeoxycholate, phosphatidylcholine and cholesterol solution under physiological conditions.

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