Abstract
Effect of vitamin E (α-tocopheryl acetate and α-tocopheryl nicotinate) on IgE antibody formation in mice was investigated. Female BALB/c mice were immunized with dinitrophenylated ascaris protein (DNP-As) and aluminium hydroxide gel (alum). Supplementation of vitamun E in diets or oral administration of vitamin E mixed with sesame oil resulted in a suppression of IgE antibody formation. On the contrary to IgE antibody formation, IgM or IgG (hemagglutinin; HA) formation was sngnifucantly enhanced. These results indicate that vitamin E is capable of suppressing IgE antibody formation and enhancing nonIgE antibody formation.
